The pharmaceutical industry is one of the most heavily regulated industries in the world. Pharmaceutical companies must adhere to strict quality standards set by regulatory agencies such as the U.S. Food and Drug Administration (FDA).
One of the most important quality criteria for pharmaceuticals is the requirement for purified water. Purified water is water that has been treated to remove impurities such as dissolved minerals, bacteria, and viruses.
This blog takes an in-depth look at different water purification methods, including distillation, reverse osmosis, and deionization, and highlights the pros and cons of each. It also outlines the various applications of purified water in the pharmaceutical industry, such as the preparation of pharmaceutical formulations, cleaning and rinsing of equipment, and quality control testing.
Pure water is treated through filtration processes to remove chemicals, contaminants, and other pollutants. After treatment, the water has no adulterations and is safe for consumption or use. Usually, groundwater or tap water is used to produce purified water. Common impurities in tap water include minerals such as calcium, magnesium, and phosphorus. These minerals are beneficial to human health to a certain extent and are completely safe to drink.
But in some industrial applications (such as the cleaning industry) tap water is not suitable. Minerals in tap water will cause some burdens on equipment in industrial use, and will also affect industrial output. In order to produce pure water for industrial production, there are special filtration systems that can effectively remove impurities and pollutants in the water.
Pure water is measured by one part per million of total dissolved solids. Generally, the measured value of tap water is about 180-320 parts per million, while the measured value of pure water is 0 parts per million or even lower.
Not all areas have access to clean and safe water, and every year people are infected with diseases and even die from unclean and unsafe drinking water. In polluted water sources, there are especially bacteria, viruses, and parasites that can cause harm to the human body, so the advantages of purity are reflected. The following are some benefits of pure water:
Hundreds of millions of people around the world don’t have access to clean water. This water is often contaminated with bacteria, sewage, and other pollutants. Drinking this water can lead to serious illnesses, including diarrhea, cholera, and typhoid. pregnant women and young children are especially vulnerable to these diseases.
One of the best ways to prevent these diseases is to use purified water. Purified water is water that has been filtered and treated to remove impurities. This process can remove many of the harmful bacteria and viruses that can cause illness.
There are many different ways to purify water, and the most effective method will depend on the quality of the water. However, some methods are more effective than others. For example, boiling water is a very effective way to kill bacteria and other pathogens. Other methods, such as filtration, can also be effective.
Clean water can also directly affect the embodiment of hygiene standards. People normally pay attention to food cleanliness and personal cleanliness in their daily lives, therefore the quality of water will catch everyone’s attention. Like we naturally clean fruits and vegetables before eating them, drinking water now needs to be purified before it can be used in a healthy manner.
In addition to drinking water to take in water, we also take in water through food, and our body may also absorb some water when we bathe. Water is inseparable from our lives. If the water is not clean and safe, the sanitation around us cannot be guaranteed. We should not only focus on the quality of drinking water, the quality of domestic water also needs to be improved.
The human body is naturally composed of 60% water, so to ensure that the water entering the human body must come from clean and safe water sources. Hydration primarily promotes cardiovascular health, lowers and regulates body temperature, softens skin, and other beneficial benefits to the body. Additionally, in order for the body’s hydration to function optimally, it must be kept well-hydrated with purified water.
Also, hydration aids in the body’s natural detoxification process. But when the body absorbs unclean or polluted water, more toxins enter the body than are excreted from the body. A harmful environment is created in the body, breeding bacteria and causing the spread of disease.
Water can contain physical (particles), chemical, and microbiological contaminants that can be harmful to human health since it has the ability to dissolve, absorb, collect, or suspend a wide variety of substances and gases.
According to the FDA, water treatment, testing, and safety are priorities in the pharmaceutical manufacturing process, particularly for microbiological quality. However, besides water that is packaged as sterile for injectable drug products, there are no absolute microbial standards for water used in pharmaceuticals.
Water is the top priority in the pharmaceutical industry. Each stage of the pharmaceutical process has different water quality requirements, and each stage has its own water type and standards.
Water used in the manufacture of pharmaceuticals and substances has at least potable water, non-potable water, and six types of USP water (USP Purified Water, USP Water for Injection (WFI), USP Sterile Water for Injection, USP Sterile Inhalation Water, USP Antimicrobial Water for Injection, USP Sterile Irrigation Water).
In the initial stage of pharmaceuticals, purified water is the first choice at this stage. This type of water has been treated to remove impurities in the water, which is directly related to the quality of the final product.
In the middle and late stages of pharmaceutical production, sterile water is used. Sterile water has been treated to remove all bacteria and contaminants from the water, which is directly related to the safety of the final product.
In the final stages of pharmaceutical production, distilled water is used. It is treated to remove all impurities (minerals and other contaminants) from the water, ensuring the purity of the final product.
Since the primary source of purified water is drinking water, it is imperative to protect the supplied water from microbial growth. No matter which type of industrial water filtration system is considered to be used in the pharmaceutical industry, the water filtration system must be disinfected regularly, and microorganisms may reproduce during the production process. Below are the different types of industrial water filtration systems that are often used in the pharmaceutical industry:
Electrodeionization is one of the most ideal types of purified water. Electrodeionization mainly involves ion exchange and electrolysis, the purpose of which is to eliminate specific ions in water and replace them with more ideal ions. This water treatment focuses on changing the ion composition in a more ideal state. The method is favored in the pharmaceutical industry due to its ease of operation and low maintenance costs.
It is widely regarded as one of the most effective methods of purifying water and is widely used in the pharmaceutical industry where water is an important resource and raw material. Reverse osmosis requires the application of pressure to the concentrated solution during osmosis, which disrupts the natural permeate flow and causes water to flow from a more concentrated solution to a less concentrated solution. Brother Filtration provides you with 8inch, 4inch and residential RO membrane for your filtration.
Distillation is primarily a process that utilizes the difference in vapor pressure of water and impurities suspended in the water. Water is boiled in a distillation unit and then condensed by steam to produce sterile, pure water. The distillation method requires a lot of energy, and the cost of this water purification method is relatively high. One of its main uses is in water for injections (a type of pharmaceutical water).
UV disinfection is a relatively simple and low-cost method of water purification. In the process of ultraviolet disinfection, ultraviolet lamps are used to expose water to ultraviolet light of a specific wavelength to eliminate bacteria and viruses in the water. It can be used not only for the manufacture of medical products but also for cleaning in place(CIP). Brother Filtration provides 3 different types of UV systems for you, which are Commercial UV Water Sterilizer, Industrial UV Water Sterilizer, and Residential UV Water Sterilizer.
Purified water exists in various stages of the production process of the pharmaceutical industry and specific operations of pharmaceutical applications, and it is widely used in the pharmaceutical industry and its applications. The pharmaceutical industry uses purified water to process and prepare drugs and some active ingredients. At the same time, purified water can also be used for product reconstitution, drug synthesis, cleaning agents, and finished product production.
Purified water has many different uses in pharmaceuticals and touches all aspects of the industry, not just cleaning equipment, but is also one of the main ingredients in many products and production processes. Its specific application is as follows:
Purified water is an essential part of the manufacturing, processing, and formulation of pharmaceuticals and APIs in the pharmaceutical industry. Purified water is inseparable from pharmaceutical production and equipment flushing in the pharmaceutical industry. Water passing through water filtration systems is effectively used in various parts of the pharmaceutical industry.
As an expert in water filtration systems, Brother Filtration can provide you with the filtration products required by different water filtration systems to fully meet your filtration needs. At the same time, we can give you professional advice and the most suitable solution to save your industrial costs. Contact us now for the best filtration solutions in the pharmaceutical industry.
